Job Description

Bioinformatics Scientist I – Inflammation

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The mission of the Allen Institute for Immunology is to advance the fundamental understanding of human immunology through the study of immune health and diseases where excessive or impaired immune responses drive pathological processes. The Institute will employ a multi-disciplinary team approach in collaboration with academic centers of human immunology to generate novel mechanistic insights into the immune synapse in health and in diseases such as autoimmunity or oncology. The Institute will simultaneously provide a foundational data set and tools for future immunological research as well as a novel collaboration portal for the broader scientific community.

The Allen Institute for Immunology is seeking a Bioinformatics Scientist I – Inflammation to analyze Spatial Biology and other OMICS data to better understand inflammatory diseases such as Inflammatory Bowel Disease (IBD). Reporting to the Director of Informatics & Computational Biology at the Allen Institute for Immunology, the ideal candidate is a self-motivated team player who can work closely with immunologists and bioinformaticians, is an expert in analyzing Spatial Biology transcriptomics, protein, and imaging data, and has a track record of discovering novel biological insights from omics data. The successful candidate will also have excellent communication skills that can represent our efforts to our stakeholders internally and in external forums.

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

Essential Functions

• Work closely with cross-functional teams to analyze Spatial Biology and other OMICS data from our Inflammation Program, generate testable hypotheses for disease mechanisms, and identify potential biomarkers and/or drug targets for disease of interest such as IBD
• Implement and/or develop analysis scripts for Spatial Biology data and other OMICS data, including but not limited to: transcriptomics, protein, and/or imaging
• Write reports, research papers, patent applications, and other documents
• Represent our efforts to our stakeholders internally and in external forums
• Contribute to a rigorously scientific, cohesive and efficient team environment

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience

• PhD in bioinformatics, biostatistics, computational biology, or closely related disciplines, or equivalent combination of degree and experience

Preferred Education and Experience

• Demonstrated experience in analyzing Spatial Biology data, including but not limited to: transcriptomics, protein, and/or imaging data
• Demonstrated experience in analyzing other OMICS data
• Knowledgeable in molecular biology and/or immunology
• Familiar with Spatial Biology technologies
• A track record of discovering novel biological insights from omics data
• Foundational knowledge of bioinformatics
• Experience with R and/or Python
• Strong publication record
• Familiar with advanced statistical methods and machine learning for biomarker discovery
• Experience working in a cross disciplinary, team-based environment
• Experience working with outside collaborators to achieve defined objectives
• Familiarity with cloud computing and/or Linux
• Experience using Git or similar version control system
• Excellent written and verbal communication skills and organizational skills
• Good problem-solving skills, curious and eager to take new challenges
• Able to work independently as well as in a collaborative high paced environment
• The successful candidate must be self-motivated, a team player, attentive to details, and able to handle multiple projects simultaneously

Work Environment

• May enter laboratory environment - possible exposure to chemical, biological, or other hazardous substances.

Physical Demands

• Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment

Position Type/Expected Hours of Work

• Occasional evening and weekend hours required
• This role is currently able to work both remotely and onsite in a hybrid work environment. We are a Washington State employer, and the primary work location for all Allen Institute employees is 615 Westlake Ave N.; any remote work must be performed in Washington State.

Travel

• Attendance and participation in national and international conferences may be required

Additional Comments

• **Please note, this opportunity offersrelocation assistance**
• **Please note, this opportunity offers work visa sponsorship**

Annualized Salary Range

• $90,900 - $112,400 *

* Final salary depends on required education for the role, experience, and level of skills relevant to the role, along with work location, where applicable.

Benefits

• Employees (and their families) are eligible to enroll in benefits per eligibility rules outline in the Allen Institute’s Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute’s 401k plan. Paid time off is also available as outlined in the Allen Institutes Benefits Guide. Details on the Allen Institute’s benefits offering are located at the following link to the Benefits Guide: https://alleninstitute.org/careers/benefits.

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.

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